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Anti-Diphtheria Toxin antibody

Anti-Diphtheria Toxin antibody

Cat no: 64-010

Supplier: B-BRIDGE INTERNATIONAL, INC
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Diphtheria toxin (535 aa, 58 kDa), is an exotoxin secreted as a proenzyme by Corynebacterium diphtheriae, the pathogen bacterium that causes diphtheria. The toxin gene is encoded by a bacteriophage. The proenzyme undergoes proteolytic nicking and reduction of disulfide bond, giving rise to subunit A (21 kDa) and B (37 kDa). Subunit B (C-terminal) recognizes cellular receptor, HB-EGF receptor, and subunit A (N-terminal) catalyzes the ADP-ribosylation of eukaryotic elongation factor-2 (eEF2), inactivating this protein.
Catalogue number: 64-010
Hosts: Rabbit
Applications: Dot Blot, ELISA, Immunoprecipitation, Western Blot
Size: 100 ug
Gene: Q5PY51
Dilutions: WB: 1:2000, ELISA 1:2,000~1:7,000 dilution (can detect 1 ng or less of the toxin), IP: 1:200~1:1,000 dilution, Dot blotting 1:1,000 dilution (can detect 1 ng or less of the toxin)
Clonality: Polyclonal
Shipping temp: 4C
Storage temp: - 20 degree C

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