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Anti-Diphtheria Toxin antibody

Cat no: 64-010

Anti-Diphtheria Toxin antibody

Diphtheria toxin (535 aa, 58 kDa), is an exotoxin secreted as a proenzyme by Corynebacterium diphtheriae, the pathogen bacterium that causes diphtheria. The toxin gene is encoded by a bacteriophage. The proenzyme undergoes proteolytic nicking and reduction of disulfide bond, giving rise to subunit A (21 kDa) and B (37 kDa). Subunit B (C-terminal) recognizes cellular receptor, HB-EGF receptor, and subunit A (N-terminal) catalyzes the ADP-ribosylation of eukaryotic elongation factor-2 (eEF2), inactivating this protein.

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SPECIFICATIONS

Catalog Number

64-010

Size

100 ug

Applications

DB, ELISA, IP, WB

Hosts

Rabbit

Gene Id

Q5PY51

Clonality

Polyclonal

Dilutions

WB: 1:2000, ELISA 1:2,000~1:7,000 dilution (can detect 1 ng or less of the toxin), IP: 1:200~1:1,000 dilution, Dot blotting 1:1,000 dilution (can detect 1 ng or less of the toxin)

Storage Temp

- 20 degree C

Shipping Temp

4C

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