Supplier:
Aviva Systems Biology IncorporatedAnti-Connexin43
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SPECIFICATIONS
Size
100 ul
Applications
WB
Hosts
Rabbit
Reactivities
Hum, Mouse, Rat, Can, Ch/Bird, Sheep, ZF/Fish
Format
Affinity purified, polyclonal antibody
Presku
OAPC00097
Target
Gap junctional intercellular communication is thought to play a key role in development and may also be involved in epilepsy (Aronica et al., 2001). Connexin43 forms gap-junctional channels and regulates the permeability of these gap junctions to small organic molecules. Permeability of connexin43 is known to be regulated by phosphorylation at er368 by protein kinase C (Yogo et al., 2002; Bao et al., 2004a). Phosphorylation of Ser368 by PKC induces a conformational change of connexin43 that results in a decrease in gap junction permeability (Bao et al., 2004b).
Weight
~43kDa
Gene Id
24392
SUPPLIER INFO
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