Supplier:
Aviva Systems Biology IncorporatedAnti-COBRA 1
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SPECIFICATIONS
Size
100 ul
Applications
WB
Hosts
Mouse
Reactivities
Hum, Mouse, Rat
Clone
F7E4
Format
Purified mouse monoclonal antibody
Presku
OAPC00093
Target
COBRA1 (cofactor of BRCA1) also known as NELF-B, is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ER alpha) and repress ER alpha -mediated transcription (Aiyar SE et al., 2004). COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogeneis (Zhong H et al., 2004)
Weight
~62kDa
Gene Id
25920
Isotype
IgG<sup>1</sup>
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