Supplier:
Aviva Systems Biology IncorporatedAnti-Cdk5(Excellent for immunohistochemistry use)
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SPECIFICATIONS
Size
100 ul
Applications
IHC, WB
Hosts
Mouse
Reactivities
Hum, Mouse, Rat
Clone
1H3
Format
Purified mouse monoclonal antibody
Presku
OAPC00088
Target
The neuronal protein kinase, Cdk5 has been implicated in a vast array of normal neuronal functions including regulation of neurotransmitter synthesis (Kansy J et al., 2004), the presynaptic vesicle cycle (Nguyen, C. & Bibb, JA 2003), neurotransmitter receptor trafficking and dopamine neurotransmission (Bibb, JA et al. 1999). At the same time Cdk5 has been implicated in a plethora of neurological and neuropsychiatric disorders including Alzheimer's, Parkinson's, Huntington's, epilepsy, schizophrenia, and drug addiction. Detection of Cdk5 in normal samples as well as tissue undergoing neurodegeneration may advance studies in these areas. Moreover, this antibody may allow more accurate postmortem evaluations of Cdk5 protein expression, and thus serve as a valuable new reagent for neuropathology.
Weight
~28kDa
Gene Id
140908
Isotype
IgG<sup>1</sup>
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