Supplier:
Aviva Systems Biology IncorporatedAnti-Calcitonin Gene Related Peptide (CGRP)
Prices direct from Aviva Systems Biology Incorporated
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SPECIFICATIONS
Size
100 ul
Applications
ICC
Hosts
Mouse
Reactivities
Hum, Rat
Format
affinity purified monoclonal antibody
Presku
OAPC00089
Target
Calcitonin Gene Related Peptide [CGRP] is a 37 amino acid peptide and is the most potent endogenous vasodilator currently known (Brain et al.,1985). CGRP is primarily produced in nervous tissue, however, its receptors are expressed throughout the body. CGRP is also strongly implicated in the vasodilatory effect of endogenous cannabinoid anandamide in the brain. This effect was found to be antagonized by capsazepine. CGRP is also currently a major target of research in regards to factors effecting the onset of migraine headaches (Edvinsson L., 2003). CGRP antibodies have been used successfully in immunoneutralization (Wong et al., 1993)
Gene Id
24241
Isotype
IgG<sup>2a</sup>
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