Presku: | AAP40204 |
Size: | 100 ug |
Weight: | 29kDa |
Gene: | 8125 |
Format: | Lyophilized powder |
Target: | ANP32A is a novel potent heat-stable inhibitor protein of protein phosphatase 2A. It may play a key role in self-renewing cell populations where it may act in the nucleus to limit their sensitivity to transformation. Being a tumor suppressor, ANP32A represses cell growth through inhibition of transcription by blocking acetylation and phosphorylation of histone H3 and initiating its proapoptotic activity. |