Reactivities: | Human |
Presku: | AAP65995 |
Size: | 100ug |
Weight: | 58kDa |
Gene: | 56899 |
Format: | Lyophilized powder |
Target: | This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene. |
Alternative names: | AIDA; AIDA-1; ANKS2; EB-1; EB1; MGC26087; cajalin-2 |