Reactivities: | Human |
Presku: | AAP42411 |
Size: | 100ug |
Weight: | 51kDa |
Gene: | 27329 |
Format: | Lyophilized powder |
Target: | The protein encoded by this gene is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis. |
Alternative names: | ANGPT5 |