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Angpt2 (angiopoietin 2 ) Blocking Peptide (the middle region of Angpt2)(100ug)

Angpt2 (angiopoietin 2 ) Blocking Peptide (the middle region of Angpt2)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-Angpt2 Antibody (ARP63170_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human, Mouse
Presku: AAP63170
Size: 100ug
Weight: 56kDa
Gene: 11601
Format: Lyophilized powder
Target: Angpt2 binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. It can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
Alternative names: Agpt2; Ang-2; Ang2
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