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ALS2 (amyotrophic lateral sclerosis 2 (juvenile)) Blocking Peptide (the middle region of ALS2)(100ug)

ALS2 (amyotrophic lateral sclerosis 2 (juvenile)) Blocking Peptide (the middle region of ALS2)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-ALS2 Antibody(ARP57487_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP57487
Size: 100ug
Weight: 184kDa
Gene: 57679
Format: Lyophilized powder
Target: The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene.
Alternative names: ALS2CR6; ALSJ; FLJ31851; IAHSP; KIAA1563; MGC87187; PLSJ
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