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Alpha-tubulin Antibody (OAPB00857)

Alpha-tubulin Antibody (OAPB00857)

Alpha-tubulin belongs to the tubulin superfamily, which is composed of six distinct families. Along with beta-tubulins, alpha-tubulins are the major components of microtubules. These microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Alpha- and beta-tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22-nm diameter. Tyrosine ligase adds a C-terminal tyrosine to monomeric alpha-tubulin. Assembled microtubules can again be detyrosinated by a cytoskeleton-associated carboxypeptidase. Another post-translational modification of detyrosinated alpha-tubulin is C-terminal polyglutamylation, which is characteristic of microtubules in neuronal cells and the mitotic spindle. Like GAPDH and beta-Actin, this antibody makes an excellent loading control in immunoblots.

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SPECIFICATIONS

Size

0.1 mg

Applications

ELISA, WB

Reactivities

Hum, Mouse, Rat

Presku

OAPB00857

Target

Tubulin alpha-1A

Alternative Names

Alpha-tubulin; Tubulin alpha-1A; TUBA1A; TUBA3; LIS3

SUPPLIER INFO

Aviva Systems Biology Incorporated

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