Home  >  Products  >  Alexa Fluor(R) 700 anti-human CD195 (CCR5)
Alexa Fluor(R) 700 anti-human CD195 (CCR5)

Alexa Fluor(R) 700 anti-human CD195 (CCR5)

Cat no: 313713

Supplier: BioLegend
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
CD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1alpha, MIP-1beta, and RANTES and is expressed on a subset of T cells and monocytes. CD195 mediates an intracellular signal thought to induce cell differentiation and proliferation. CCR5 has also been shown to act as a co-receptor for R5 HIV-1 cell entry; modification of CCR5 by sulfation contributes to the efficiency of HIV-1 entry. Recent studies have shown CCR5 to play a role in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer.
Catalogue number: 313713
Reactivities: Human
Hosts: Rat
Applications: Flow Cytometry
Size: 25 microg
Clone: HEK/1/85a
Gene: 1234
Dilutions: This reagent is developed for immunofluorescent staining for flow cytometric analysis; the suggested use of this reagent is ?2.0 microg per million cells in 100 microl volume. It is highly recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor(R) 700 has a maximum emission of 719 nm when it is excited at 633 nm / 635 nm. Prior to using Alexa Fluor(R) 700 conjugate for flow cytometric analysis, please verify your flow cytometer's capability of exciting and detecting the fluorochrome.** Alexa Fluor(R) 700 is a registered trademark of Molecular Probes, Inc. Alexa Fluor(R) 700 dye antibody conjugates are sold under license from Molecular Probes, Inc. for research use only, except for use in combination with microarrays and high content screening, and are covered by pending and issued patents.
Storage buffer: The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Concentration: 0.5 mg/ml
Antigen: CHO cells transfected with human CCR5
Isotype: Rat IgG2a, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: CCR5, C-C chemokine receptor type 5, HIV-1 fusion co-receptor
See Full Product Listings >