Alexa Fluor(R) 700 anti-human CD158e1 (KIR3DL1, NKB1)

NKB1 is a 70 kD member of the immunoglobulin superfamily that is expressed on a subset of natural killer cells and T cells at varying levels among individuals. NKB1 is a type I membrane protein containing two immunoglobulin C2-type domains. The interaction of NKB1 with specific HLA-B antigens on a target cell (the HLA-Bw4 allele, for example) inhibits cytotoxicity and prevents target cell lysis and death. The interactions between KIR and MHC class I are thought to be important in NK and T cell regulation following antigen stimulation. The absence of ligands for KIRs may lower the threshold for activation through activating receptors and increase inflammation and susceptibility to autoimmune disease.

Prices direct from BioLegend

Quick response times

Exclusive Absave savings/discounts

SPECIFICATIONS

Catalog Number

312711

Size

25 microg

Applications

FC

Hosts

Mouse

Reactivities

Hum

Clone

DX9

Antigen

Human NK cell clone VL186-1.6

Gene Id

3811

Isotype

Mouse IgG1, kappa

Clonality

Monoclonal

Dilutions

This reagent is developed for immunofluorescent staining for flow cytometric analysis; the suggested use of this reagent is ?0.125 microg per million cells in 100 microl volume. It is highly recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor(R) 700 has a maximum emission of 719 nm when it is excited at 633 nm / 635 nm. Prior to using Alexa Fluor(R) 700 conjugate for flow cytometric analysis, please verify your flow cytometer's capability of exciting and detecting the fluorochrome.** Alexa Fluor(R) 700 is a registered trademark of Molecular Probes, Inc. Alexa Fluor(R) 700 dye antibody conjugates are sold under license from Molecular Probes, Inc. for research use only, except for use in combination with microarrays and high content screening, and are covered by pending and issued patents.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.

Alternative Names

NKAT3, NKB1, KIR-NKB1, p70

Regulatory Status

RUO