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Alexa Fluor(R) 647 anti-mouse CD226 (DNAM-1)

Alexa Fluor(R) 647 anti-mouse CD226 (DNAM-1)

Cat no: 128808

Supplier: BioLegend
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CD226 (DNAM-1) is constitutively expressed on native CD8+ cells and on CD4+ T cells,macrophages and NK cells.This antibody (10E5) was reported to bind about 40% of inactivated CD4+ cells and binds only to differentiated Th1 cells, but not to Th2 or Th0 cells.It is also reported to suppress antigen-specific T cell expansion and EAE(experimental allergic encephalitis) mediated by Th1 cells.
Catalogue number: 128808
Reactivities: Mouse
Hosts: Rat
Applications: Flow Cytometry
Size: 100 microg
Clone: 10E5
Gene: 22582
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.25 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor(R) 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm.** Alexa Fluor(R) 647 is a registered trademark of Molecular Probes, Inc. Alexa Fluor(R) 647 dye antibody conjugates are sold under license from Molecular Probes, Inc. for research use only, except for use in combination with microarrays and high content screening, and are covered by pending and issued patents.
Storage buffer: The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Concentration: 0.5 mg/ml
Antigen: Th1 polarized T cell clones
Isotype: Rat IgG2b
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: DNAM-1, PTA1(platelet and T cell activation antigen 1), TLISA1, LFA-1 associated Molecule PTA-1
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