Alexa Fluor(R) 647 anti-Human Podoplanin

Podoplanin is a 40-43 kD type-I transmembrane sialomucin-type glycoprotein, also known as T1a, gp36, gp38, gp40, or Aggrus. Originally detected on the surface of podocytes, futher characterization showed podoplanin has a broad tissue distribution including many mesothelial cells, epithelial cells, follicular dendritic cells and a variety of tumor cells. It has been reported that podoplanin is the ligand of CLEC-2 and is involved in lymphatic vessel formation, platelet aggregation, and tumor metastasis. Podoplanin may serve as a useful marker for tumor diagnosis and prognosis.

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SPECIFICATIONS

Catalog Number

337007

Size

25 tests

Applications

FC

Hosts

Rat

Reactivities

Hum

Clone

NC-08

Gene Id

10630

Isotype

Rat IgG2a, lambda

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 microl per million cells or 5 microl per 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor(R) 647 has a maximum emission of 668 nm when it is excited at 633nm / 635nm.** Alexa Fluor(R) is a registered trademark of Molecular Probes, Inc. Alexa Fluor(R) dye antibody conjugates are sold under license from Molecular Probes, Inc. for research use only, except for use in combination with microarrays and high content screening, and are covered by pending and issued patents.

Storage Temp

4 C

Concentration

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.

Alternative Names

T1a, gp38, stromal cell marker

Regulatory Status

RUO