Alexa Fluor(R) 647 anti-human IL-1beta

IL-1 refers to two proteins, IL-1alpha and IL-1beta which are the products of distinct genes, but which are recognized by the same cell surface receptors. IL-1beta is a potent immuno-modulator which mediates a wide range of immune and inflammatory responses including the activation of B and T cells. The JK1B-1 antibody reacts with human interleukin-1beta (IL-1beta) and baboon IL-1beta. The JK1B-1 antibody does not recognize mouse IL-1beta or human IL-1alpha or other cytokines. The JK1B-1 antibody can neutralize the bioactivity of natural or recombinant IL-1beta.

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SPECIFICATIONS

Catalog Number

508208

Size

100 tests

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

Clone

JK1B-1

Antigen

Recombinant human IL-1 beta

Gene Id

3553

Isotype

Mouse IgG

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 microl per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor(R) 647 has a maximum emission of 668 nm when it is excited at 633nm / 635nm.** Alexa Fluor(R) is a registered trademark of Molecular Probes, Inc. Alexa Fluor(R) dye antibody conjugates are sold under license from Molecular Probes, Inc. for research use only, except for use in combination with microarrays and high content screening, and are covered by pending and issued patents.

Storage Temp

4 C

Concentration

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.

Alternative Names

Interleukin-1beta, Catabolin, Hematopoietin-1 (H1), IFNbeta-inducing factor, Interleukin-beta, Osteoclast activating factor (OAF), IL-1beta, IL1beta, IL 1beta, il1 beta

Regulatory Status

RUO