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Aldh5A1 Antibody (OAPB00755)

Aldh5A1 Antibody (OAPB00755)

Aldh5A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh5A1 is a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, results in a disorder of the neurotransmitter 4-aminobutyric acid (GABA). Symptoms usually include static encephalopathy, associated with developmental delays, hypotonia, ataxia, speech defects, and seizures. At least two isoforms of Aldh5A1 are known to exist.

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SPECIFICATIONS

Size

0.1 mg

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Presku

OAPB00755

Target

Aldehyde dehydrogenase family5 member A1

Alternative Names

Aldh5A1;Aldehyde dehydrogenase family5 member A1; succinate-semialdehyde dehydrogenase; SSDH; SSADH

SUPPLIER INFO

Aviva Systems Biology Incorporated

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