Presku: | AAP54346 |
Size: | 100 ug |
Weight: | 70kDa |
Gene: | 211 |
Format: | Lyophilized powder |
Target: | Delta-aminolevulinate synthase (ALAS; EC 2.3.1.37) catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2. |
Alternative names: | ALAS; ALAS3; ALASH; MIG4 |