Reactivities: | Human |
Presku: | AAP41845 |
Size: | 100ug |
Weight: | 39kDa |
Gene: | 210 |
Format: | Lyophilized powder |
Target: | The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. |
Alternative names: | ALADH; MGC5057; PBGS |