Home  >  Products  >  AIRE (autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)) Blocking Peptide (100ug)
AIRE (autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)) Blocking Peptide (100ug)

AIRE (autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)) Blocking Peptide (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-AIRE antibody (Catalogue #: ARP32650_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP32650
Size: 100 ug
Weight: 58kDa
Gene: 326
Format: Lyophilized powder
Target: The function of the protein encoded by the AIRE gene is not well defined. However it contains zinc finger motifs suggestive of a transcription factor. The protein (isoform 1) is localized to both the nucleus and cytoplasm. Defects in this gene cause the autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript predicted to be a candidate for nuclear-mediated decay (NMD). Defects in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).
Alternative names: AIRE1; APECED; APS1; APSI; PGA1
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