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AGE Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251527

AGE Antibody

Advanced Glycation End products (AGEs) are the result of a chain of chemical reactions after an initial glycation reaction. The intermediate products are known, variously, as Amadori, Schiff base and Maillard products, named after the researchers who first described them. The formation and accumulation of advanced glycation endproducts (AGEs) has been implicated in the progression of age-related diseases. They are recognized as photosensitizers in the crystalline lens through crosslinking which has implications for cataract development. AGEs have been implicated in Alzheimer's disease, cardiovascular disease, and stroke. The mechanism by which AGEs induce damage is through a process called cross-linking that causes intracellular damage and apoptosis. Reduced muscle function is also associated with AGEs.

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SPECIFICATIONS

Catalog Number

251527

Size

0.1 mg

Applications

IHC

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

Glycoaldehyde-modified proteins.

Isotype

Rabbit Ig

Additional Info

AGE; AGEs; Advanced Glycated End Product; Advanced Glycation End Products

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