Reactivities: | Human |
Presku: | AAP51965 |
Size: | 100ug |
Weight: | 79kDa |
Gene: | 156 |
Format: | Lyophilized powder |
Target: | The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. |
Alternative names: | BARK1; BETA-ARK1; FLJ16718; GRK2 |