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ADAMTS4 (ADAM metallopeptidase with thrombospondin type 1 motif, 4) Blocking Peptide (100ug)

ADAMTS4 (ADAM metallopeptidase with thrombospondin type 1 motif, 4) Blocking Peptide (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-ADAMTS4 antibody (Catalogue #: ARP41556_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP41556
Size: 100 ug
Weight: 37kDa
Gene: 9507
Format: Lyophilized powder
Target: ADAMTS4 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. ADAMTS4 lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.
Alternative names: ADAMTS-2, ADAMTS-4, ADMP-1, KIAA0688
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