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ADAM-TS7 Antibody

ADAM-TS7 Antibody

Cat no: 250456

Supplier: ABBIOTEC
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A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS7) is a metalloprotease that degrades COMP. ADAM-TS7 is up-regulated in articular cartilage and synovium from arthritis patients. The spacer domain and the thrombospondin type-1 domain are important for a tight interaction with the e, Xenopus/Amphibian,tracellular matri, Xenopus/Amphibian,. The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
Catalogue number: 250456
Reactivities: Human, Mouse, Rabbit
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: Q9UKP4
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ADAM-TS7.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: A disintegrin and metalloproteinase with thrombospondin motifs 7; ADAMTS-7; ADAM-TS 7; ADAM-TS7; COMPase; ADAMTS7
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