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?-Actinin (sarcomeric) Antibody
ABBIOTEC

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ABBIOTEC

Cat no: 251811

?-Actinin (sarcomeric) Antibody

Alpha actinin (?-actinin) is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle ?-actinin isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.

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SPECIFICATIONS

Catalog Number

251811

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Mouse Monoclonal Antibody

Antigen

Rabbit skeletal a-actinin.

Isotype

Mouse IgG1

Accession

Q07931

Clonality

SA-20

Additional Info

Alpha-actinin-1; Alpha-actinin cytoskeletal isoform; F-actin cross-linking protein; Non-muscle alpha-actinin-1; ACTN1

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