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ABL1 (7B11) Antibody

ABL1 (7B11) Antibody

Cat no: 252799

Supplier: ABBIOTEC
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c-ABL (Proto-oncogene c-Abl) is a protein kinase that regulates key processes linked to cell growth and survival. c-ABL regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. C-ABL localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. c-ABL regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. A chromosomal aberration involving c-ABL1 is a cause of chronic myeloid leukemia.
Catalogue number: 252799
Reactivities: Human
Applications: Western Blot
Size: 0.1 ml
Accession: P00519
Antigen: Purified recombinant fragment of ABL1(aa577-650) e, Xenopus/Amphibian,pressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type: Mouse Monoclonal Antibody
Isotype: Mouse IgG1
Clonality: 7B11D6
Additional info: ABL1; Abelson murine leukemia viral oncogene homolog 1; Proto-oncogene tyrosine-protein kinase ABL1; c-ABL; p150; ABL
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