Reactivities: | Human |
Presku: | AAP61420 |
Size: | 100ug |
Weight: | 52kDa |
Gene: | 10152 |
Format: | Lyophilized powder |
Target: | ABI2 may act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. ABI2 is a part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. It regulates ABL1/c-Abl-mediated phosphorylation of MENA. |
Alternative names: | ABI-2; ABI2B; AIP-1; AblBP3; SSH3BP2; argBPIA; argBPIB |