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ABCE1 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251983

ABCE1 Antibody

ATP-binding cassette sub-family E member 1 (ABCE1) antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. ABCE1 plays a central role in the regulation of mRNA turnover. ABCE1 antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway, an acts as a chaperone for post-translational events during HIV-1 capsid assembly.

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SPECIFICATIONS

Catalog Number

251983

Size

0.1 mg

Applications

WB

Reactivities

Hum

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human ABCE1.

Isotype

Rabbit Ig

Accession

P61221

Additional Info

ATP-binding cassette sub-family E member 1; RNase L inhibitor; Ribonuclease 4 inhibitor; RNS4I; 2'-5'-oligoadenylate-binding protein; HuHP68; ABCE1; RLI; RNASEL1; RNASELI; RNS4I

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