

Supplier:
Aviva Systems Biology IncorporatedABCD2 (ATP-binding cassette, sub-family D (ALD), member 2) Blocking Peptide (the N terminal of ABCD2)(100ug)
Prices direct from Aviva Systems Biology Incorporated
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Exclusive Biosave savings/discounts
SPECIFICATIONS
Size
100ug
Reactivities
Hum
Format
Lyophilized powder
Presku
AAP43657
Target
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis.
Weight
83kDa
Gene Id
225
Alternative Names
ABC39; ALDL1; ALDR; ALDRP; hALDR
Applications
ELISA
Hosts
Mouse
Reactivities
Rat
Applications
ELISA
Hosts
Mouse
Applications
FC
Hosts
Mouse
Reactivities
Hum
Applications
ELISA, WB
Hosts
Mouse
Reactivities
Hum
Applications
ELISA, IHC
Hosts
Mouse
Reactivities
Hum
Applications
ELISA
Hosts
Mouse
Reactivities
Hum
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