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AATF Antibody

AATF Antibody

Cat no: 251597

Supplier: ABBIOTEC
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Protein AATF (AATF) functions as a general inhibitor of the histone deacetylase HDAC1. The binding of AATF to the pocket region of RB1 may displace HDAC1 from RB1/E2F comple, Xenopus/Amphibian,es, leading to activation of E2F target genes and cell cycle progression. Conversely, displacement of HDAC1 from SP1 bound to the CDKN1A promoter leads to increased e, Xenopus/Amphibian,pression of this CDK inhibitor and blocks cell cycle progression. AATF also antagonizes PAWR mediated induction of aberrant amyloid peptide production in Alzheimer
Catalogue number: 251597
Reactivities: Human, Mouse, Rabbit
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: Q9NY61
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human AATF.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: AATF; Protein AATF; Apoptosis-antagonizing transcription factor; Rb-binding protein Che-1; CHE1; DED
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