Home  >  Products  >  4E-BP1 (11G1) Antibody
4E-BP1 (11G1) Antibody

4E-BP1 (11G1) Antibody

Cat no: 252682

Supplier: ABBIOTEC
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
4E-BP1 (Eukaryotic translation Initiation Factor 4E Binding Protein 1) is a 118-amino acid protein (~13kDa). Binding of eIF4EBP1 to eIF4E is reversible and is dependent on the phosphorylation status of eIF4EBP1. Non phosphorylated eIF4EBP1 will bind strongly to eIF4E while the phosphorylated form will not. Akt, TOR,Mouse,AP kinase, S6 kinase and Cdc2 are known kinases capable of inactivating eIF4EBP1 binding to eIF4E by phosphorylating either threonines 35, 45, 69 or serine 64. Although, not all phosphorylation events equally block the eIF4EBP1-eIF4E interaction.
Catalogue number: 252682
Reactivities: Human
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: Q13541
Antigen: Purified recombinant fragment of 4EBP1 e, Xenopus/Amphibian,pressed in E. coli.
Format: Each vial contains 0.1 mg IgG in PBS pH7.4 with 0.03% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Mouse Monoclonal Antibody
Isotype: Mouse IgG1
Clonality: 11G12C11
Additional info: Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I; EIF4;EBP1
See Full Product Listings >