Reactivities: | Human, Mouse |
Presku: | AAP57205 |
Size: | 100ug |
Weight: | 52kDa |
Gene: | The peptide is characterized by mass spectroscopy |
Format: | Lyophilized powder |
Target: | 4930506M07Rik is involved in the generation of internal asymmetric signals required for neuronal polarization. It acts upstream of PI3K (phosphoinositide 3-kinase), by being required for spatially localized PI3K Activity. 4930506M07Rik accumulates asymmetrically in a single neurite before polarization, leading to axon induction for polarization, its absence from the nascent axon's siblings by competition preventing the formation of surplus axons. |
Alternative names: | KIAA1598; Shootin1; mKIAA1598 |