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2410015M20Rik (RIKEN cDNA 2410015M20 gene ) Blocking Peptide (the C terminal of 2410015M20Rik)(100ug)

2410015M20Rik (RIKEN cDNA 2410015M20 gene ) Blocking Peptide (the C terminal of 2410015M20Rik)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-IL24 Antibody (ARP53387_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP53387
Size: 100ug
Weight: 22kDa
Gene: 11009
Format: Lyophilized powder
Target: This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alternative names: C49A; FISP; IL-24; IL10B; MDA7; Mob-5; ST16; mda-7
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