2410015M20Rik (RIKEN cDNA 2410015M20 gene ) Blocking Peptide (the C terminal of 2410015M20Rik)(100ug)

This is a synthetic peptide designed for use in combination with anti-IL24 Antibody (ARP53387_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

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SPECIFICATIONS

Size

100ug

Reactivities

Hum

Format

Lyophilized powder

Presku

AAP53387

Target

This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Weight

22kDa

Gene Id

11009

Alternative Names

C49A; FISP; IL-24; IL10B; MDA7; Mob-5; ST16; mda-7