Antibodies
Looking to buy reliable and cost effective Antibodies for your research?
Antibodies are protein molecules used by an organism’s immune system to bind to and deactivate a foreign molecule, or antigen, such as a virus or a drug. The 3-dimensional shape of the antibody must fit the epitope on the surface of an antigen, in order to bind with that antigen to prevent it from harming the organism, or to tag it for destruction.
Since their discovery in 1890, antibodies have become the workhorses of the lab in genetic, protein, biochemical and other research, as well as for drug development, therapeutics and diagnosing infectious diseases. In the lab, antibodies are used to detect specific proteins. For example, new methods are being developed that use antibodies to detect cancer cells in a patient’s bloodstream.
Humans alone create billions of different antibodies, while other organisms such as mice, goats, chickens, plants, viruses and insects generate billions more. Thousands of these antibodies are available to researchers in purified commercial preparations.
For research or clinical testing, antibodies are prepared by injecting an antigen into a living host, such as a mouse, which reacts by creating large amounts of antibodies that must then be extracted for use. The host species used is just one of several considerations for choosing a particular antibody for a given assay. Another consideration is the target gene or protein to be studied, including the specific part and isoform of the protein.
Antibodies come in primary and secondary types. Primary antibodies react to the presence of an antigen. Secondary antibodies, labeled “anti-human” or “anti-mouse,” etc., bind to the primary antibodies. The secondary antibody can be designed so that an identifying marker allows a clinician or researcher to detect the presence of and/or measure the amount of the antibody.
Browse the product range below or simply use the Search Tool above to help find the best Antibodies at the most competitive prices.
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