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Products Slo2.1/ SLICK potassium channel, S11-33
| Catalogue number: | SMC-324D |
| Reactivities: | Mouse, Rat |
| Hosts: | Mouse |
| Applications: | Immunohistochemistry, Western Blot |
| Size: | 100ug |
| Clone: | S11-33 |
| Accession: | NP_940905.2 |
| Gene: | 343450 |
| Swiss prot: | Q6UVM3 |
| Dilutions: | 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF) |
| Form: | Protein G Purified |
| Storage buffer: | PBS pH7.4, 50% glycerol |
| Concentration: | 1mg/mL |
| Isotype: | IgG1 |
| Shipping temp: | Blue Ice or 4 |
| Storage temp: | -20 |
| Research area: | Channels and Transporters |
| Certificate of analysis: | 1ug/mL of SMC-324 was sufficient for detection of Slo2.1 in 10ug of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. |
| Scientific background: | Slo2.1 is a novel member of the mammalian Slo potassium channel gene family (3). The slick channel is activated by intracellular Na+ and Cl- and is inhibited by intracellular ATP. It is also widely expressed in the CNS and detected in the heart (4). |
| Alternative names: | KCNT2, KCa4.2, SLICK, Slo2.1, sodium and chloride activated ATP sensitive potassium channel Slo2.1 |
| References: | 1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA. 2. www.iochannels.org 3. Santi C.M., et al. (2006) J Neuroscience 26(19): 5059- 5068. 4. Bhattacharjee A., et al. (2003) J Neuroscience 23(37): 1 |
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