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HIF1 alpha, ESEE122

HIF1 alpha, ESEE122

Cat no: SMC-184D


Supplier: StressMarq Biosciences Inc.
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Specific for HIF1Alpha
Catalogue number: SMC-184D
Reactivities: Human, Mouse, Rat, Bovine
Hosts: Mouse
Applications: ELISA, Immunocytochemistry, Immunohistochemistry
Size: 100ug
Clone: ESEE122
Accession: NP_034561.2
Gene: 15251
Swiss prot: Q61221
Dilutions: 1:1000-1:8000 (IHC), 8-21ug/mL (ICC/IF)
Form: Protein G purified
Storage buffer: PBS pH7.4, 50% glycerol
Concentration: 1mg/mL
Isotype: IgG1
Shipping temp: Blue Ice or 4
Storage temp: -20
Research area: Oxidative Stress/Cell Signaling
Certificate of analysis: 1 ug/mL of SMC-184 was sufficient for detection of HIF1(A) in 20ug of CoCl2-induced Hela cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Scientific background: Hypoxia-inducible factor 1 (HIF1) is a heterodimeric transcription factor that plays a critical role in the cellular response of hypoxia (1). The HIF1 complex consists of two subunits, HIF1-Alpha and HIF1-Beta, which are basic helix-loop-helix proteins of
Alternative names: ARNT interacting protein, HIF1A, Hypoxia inducible factor 1 alpha, MOP1, PASD8
References: 1. Sharp F.R. and Bernaudin M. (2004) Nat Rev Neurosci 5, 437-48. 2. Wang G.L., et al. (1995) Proc Natl Acad Sci U S A 92, 5510-4. 3. Jaakkola P., et al. (2001) Science 292, 468-72. 4. Maxwell P.H., et al. (1999) Nature 399, 271-5. 5. Fukuda R., et al. (2