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HIF2 alpha, EP190b

HIF2 alpha, EP190b

Cat no: SMC-185C


Supplier: StressMarq Biosciences Inc.
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Human
Catalogue number: SMC-185C
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot
Size: 25ug
Clone: EP190B
Accession: NP_001421.4
Gene: 2034
Swiss prot: Q99814
Dilutions: 1:100-1:500 (WB)
Form: Protein G Purified
Storage buffer: PBS pH7.4, 50% glycerol
Concentration: 1mg/mL
Isotype: IgG1
Shipping temp: Blue Ice or 4
Storage temp: -20
Research area: Oxidative Stress/Cell Signaling
Certificate of analysis: 1 ug/mL of SMC-185 was sufficient for detection of HIF2(A) in 20ug of CoCl2-induced Hela cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Scientific background: Members of the hypoxia-inducible factor (HIF) family of transcription factors regulate the cellular response to hypoxia (1). HIF2-Alpha is involved in catecholamine homeostasis, vascular remodeling, physiological angiogenesis and adipogenesis. It is overe
Alternative names: ECYT4, EPAS1, HIF2alpha, HIF1 Alpha like factor, HLF, Hypoxia inducible factor 2 alpha, MOP2, PASD2
References: 1. Kim W.Y., et al. (2009) J Clin Invest. 119(8): 2160-2170. 2. Favier J., Lapointe S., Maliba R. and Sirois M.G. (2007) BMC Cancer. 7:139. 3. Imtiyaz H.Z., et al. (2010) J Clin Invest. 120(8): 2699-2714.