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Rhodopsin

Rhodopsin

Cat no: SMC-177D


Supplier: StressMarq Biosciences Inc.
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~40kDa.
Catalogue number: SMC-177D
Hosts: Mouse
Applications: ELISA, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100ug
Clone: 1D4
Accession: NP_000530.1
Gene: 6010
Swiss prot: P08100
Dilutions: 1:1000 (WB)
Form: Protein G Purified
Storage buffer: PBS pH7.4, 50% glycerol
Concentration: 1mg/mL
Isotype: IgG1
Shipping temp: Blue Ice or 4
Storage temp: -20
Research area: Signaling, GTPase
Certificate of analysis: 1 ug/mL of SMC-177 was sufficient for detection of rhodopsin in 10ug of rat eye lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Scientific background: Rhodopsin consists of the protein moiety opsin and a reversibly covalently bound cofactor, retinal. Opsin, a bundle of seven membrane embedded alpha-helices, binds retinal, a photoreactive chromophore, in a central pocket (2, 3). In addition to being the
Alternative names: OPN2, opsd, opsin 2, opsin 2 rod pigment, opsin2, RHO, RP4, MGC138309, Retinitis Pigmentosa 4
References: 1. Molday R.S., Hicks D., and Molday L. (1987) Invest Ophthalmol Vis Sci. 28: 50-61. 2. Ridge K.D., Lee S.S.J., and Abdulaev N.G. (1996) J of Biol Chem. 271: 7860-7867. 3. Matsuyama T., Yamashita T., Imai H. and Shichida Y. (2009) J Biol Chem. Manuscript