Monoclonal Anti-P-Glycoprotein (MDR)

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SPECIFICATIONS

Price

200.00 USD

Catalog Number

MA1060

Size

100ug/vial

Applications

ICC, IHC, IHC-Fr, WB

Reactivities

Hum

Form

Lyophilized

Format

1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Gene Id

Human(5243), Mouse(18671), Rat(170913)

Swiss Prot

Human(P08183), Mouse(P21447), Rat(P43245)

Storage Temp

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Target Synonym

CLCS; MDR1; P-GP; PGY1; ABC20; CD243; GP170; ATP-binding cassette sub-family B member 1;\nP-glycoprotein 1\n \n

Primary Protein

Multidrug resistance protein 1\n

Scientific Background

P-Glycoprotein,, also known as Multidrug Resistance 1 (MDR1), is one of the ATP-binding cassette tra\nnsporters family. P-glycoprotein-1 is involved in the transport of 3 of these protease inhibitors in vitro. MDR1 gene is mapped to the 7q21.1 by in situ hybridization. The MDR1 gene product, P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin.