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Polyclonal Anti-rat IL-10

Cat no: RP1016


Supplier: Boster Immunoleader
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Rabbit IgG polyclonal antibody for Interleukin-10 (IL10) detection. Tested with WB, IHC-P, ELISA in Rat.
Catalogue number: RP1016
Price: $240.00
Reactivities: Rat
Applications: ELISA, Immunohistochemistry, Western Blot
Size: 100ug/vial
Gene: IL10
Swiss prot: P29456
Form: Lyophilized
Format: Each vial contains 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Storage temp: "At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing. "
Scientific background: Interleukin-10 (IL-10 or IL10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. In humans IL-10 is encoded by the IL10 gene. It is capable of inhibiting synthesis of pro-inflammatory cytokines like IFN-gamma, IL-2, IL-3, TNFalpha and GM-CSF made by cells such as macrophages and regulatory T-cells.IL-10 also displays potent abilities to suppress the antigen presentation capacity of antigen presenting cells. Kim et al. (1992) showed that the mouse Il 10 gene contains 5 exons and spans about 5.2 kb of genomic DNA. Eskdale et al. (1997) mapped the IL10 gene to the junction between 1q31 and 1q32.
References: 1. Eskdale J, Kube D, Tesch H, Gallagher G (1997). "Mapping of the human IL10 gene and further characterization of the 5' flanking sequence".
Additional info: E. coli-derived rat IL-10 recombinant protein (Position: S19-N178).