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Products Monoclonal Anti-Cdk7/CAK
| Catalogue number: | MA1022 |
| Price: | $200.00 |
| Reactivities: | Human |
| Applications: | Immunocytochemistry, Immunohistochemistry - frozen, Western Blot |
| Size: | 100ug/vial |
| Gene: | Human(1022), Mouse(12572), Rat(171150) |
| Swiss prot: | Human(P50613), Mouse(Q03147), Rat(P51952) |
| Form: | Lyophilized |
| Format: | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml. |
| Target synonym: | CAK; CDKN7; MO15; CAK1; STK1; p39 Mo15; KINASE SUBUNIT OF CAK; SERINE/THREONINE PROTEIN KINASE 1; CELL DIVISION PROTEIN KINASE 7;39 kDa protein kinase; CDK-activating kinase 1; Cell division protein kinase 7;Serine/threonine-protein kinase 1; TFIIH basal transcription factor complex kinase subunit |
| Storage temp: | At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing. |
| Primary protein: | Cyclin-dependent kinase 7 |
| Scientific background: | CDK-activating kinases (CAKs) are multisubunit proteins that phosphorylate and thus activate certain cyclin-dependent protein kinases in the regulation of cell cycle progression. Cyclin dependent kinase7( CDK7) gene is mapped to chromosome 2p15-cen. CDK7 functions in both cyclin binding and T-loop phosphorylation and that these 2 steps of CDK1 activation are mutually dependent. |
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