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Monoclonal Anti-c-Myc

Cat no: MA1028


Supplier: Boster Immunoleader
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Catalogue number: MA1028
Price: $200.00
Reactivities: Human
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Size: 100ug/vial
Gene: Human(4609), Mouse(17869), Rat(24577)
Swiss prot: Human(P01106), Mouse(P01108), Rat(P09416)
Form: Lyophilized
Format: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.
Target synonym: C-Myc; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64; Class E basic helix-loop-helix protein 39;
Storage temp: At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Primary protein: Myc proto-oncogene protein
Scientific background: C-Myc is an oncogene that functions both in the stimulation of cell proliferation and in apoptosis. c-Myc elicits its oncogenic activity by causing immortalization, and to a lesser extent the transformation of cells, in addition to several other mechanisms. The c-MYC proto-oncogene encodes a transcription factor that is critical for cell growth and proliferation. It is one of the genes frequently altered in cancer cells in which it exhibits constitutive activity. Downregulation of c-Myc is critical for 2-Methoxyestradiol (2ME2)-induced oxidative stress and apoptosis in AML cells. And its up-regulation is important for promoting lymphocyte cell division, and demonstrating that GFP-c-Myc expression is a marker of proliferating lymphocytes in vivo.