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KV3.4, S72-16

KV3.4, S72-16

Cat no: SMC-335D


Supplier: StressMarq Biosciences Inc.
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Detects ~70kDa (100kDa in brain due to glycosylation)
Catalogue number: SMC-335D
Reactivities: Human, Mouse
Hosts: Mouse
Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100ug
Clone: S72-16
Accession: NP_001116248.1
Gene: 684516
Swiss prot: Q63734
Dilutions: 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF)
Form: Protein G Purified
Storage buffer: PBS pH7.4, 50% glycerol
Concentration: 1mg/mL
Isotype: IgG1
Shipping temp: Blue Ice or 4
Storage temp: -20
Research area: Ion Channels
Certificate of analysis: 1ug/mL of SMC-335 was sufficient for detection of Kv3.4 in 10ug of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Scientific background: Kv3.4, a member of the Shaw subfamily, may play important roles in maintaining normal function of the corneal epithelium (3). Kv3.4 is also over-expressed in the early stages of Alzheimer
References: 1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA. 2. www.iochannels.org 3. Wang L., Fyffe R.E.W., and Lu L. (2004) Investigative Ophthalmology and Visual Science. 45: 1796-1803. 4. Angulo E., et