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Kir2.1, S112B-14

Kir2.1, S112B-14

Cat no: SMC-310D


Supplier: StressMarq Biosciences Inc.
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Detects ~45kDa. No cross-reactivity against Kir2.2 or Kir2.3
Catalogue number: SMC-310D
Reactivities: Human, Mouse, Rat
Hosts: Mouse
Applications: Immunohistochemistry, Western Blot
Size: 100ug
Clone: S112B-14
Accession: NP_032451
Gene: 16518
Swiss prot: P35561
Dilutions: 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF)
Form: Protein G purified
Storage buffer: PBS pH7.4, 50% glycerol
Concentration: 1mg/mL
Isotype: IgG1
Shipping temp: Blue Ice or 4
Storage temp: -20
Research area: Channels and Transporters
Certificate of analysis: 1 ug/mL of SMC-310 was sufficient for detection of Kir2.1 in 10ug of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Scientific background: The Kir2.1 inward-rectifier potassium ion channel is encoded by the KCNJ2 gene. A defect in this gene is associated with Andersen-Tawil syndrome (3).
Alternative names: HHBIRK1, HHIRK1, HIRK 1, IRK1, KCNJ2, LQT7, SQT3, potassium inwardly rectifying channel J2
References: 1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA. 2. www.iochannels.org 3. Donaldson M.R., Yoon G., Fu Y.H., Ptacek L.J. (2004). Ann. Med. 36 Suppl 1: 92