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Hsp90 complex

Hsp90 complex

Cat no: SMC-109A


Supplier: StressMarq Biosciences Inc.
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Immunoprecipitates 90kDa proteins corresponding to the molecular mass of Hsp90. Co-immunoprecipitates Hsp90 complexes, including Hsp70, Hop, Ah receptors, glucocorticoid receptors, heme-regulated eukaryotic initiation factor 2(A) (eIF-2(A)) kinase (HRI).
Catalogue number: SMC-109A
Reactivities: Human, Mouse, Rat
Hosts: Mouse
Applications: Immunoprecipitation
Size: 50ug
Clone: 8D3
Accession: NP_031381.2
Gene: 3326
Swiss prot: P08238
Form: PEG Purified
Storage buffer: PBS, 50% glycerol
Concentration: 1mg/mL
Isotype: IgM
Shipping temp: Blue Ice or 4
Storage temp: -20
Research area: Heat Shock
Certificate of analysis: Goat anti-mouse IgM was used to bind 25 ul of protein G-Sepharose. SMC-109 IgM from 0.5 ml of high speed supernatant medium was loaded onto the IgG resin and incubated with 100 ul of rabbit reticulocyte lysate for 30 min. at 30C. After washing (4X1 ml), b
Scientific background: Hsp90 is a highly conserved and essential stress protein that is expressed in all eukaryotic cells. From a functional perspective, hsp90 participates in the folding, assembly, maturation, and stabilization of specific proteins as an integral component of
References: 1. Arlander SJH, et al. (2003) J Biol Chem 278: 52572-52577. 2. Pearl H, et al. (2001) Adv Protein Chem 59:157-186. 3. Neckers L, et al. (2002) Trends Mol Med 8:S55-S61. 4. Pratt W, Toft D. (2003) Exp Biol Med 228:111-133. 5. Pratt W, Toft D. (1997) Endoc