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GRP94

GRP94

Cat no: SMC-105A


Supplier: StressMarq Biosciences Inc.
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Detects a 98kDa protein corresponding to the molecular mass of Grp94 on SDS PAGE immunoblots. Does not detect human Hsp90, Grp74, or GrpE from E.coli.
Catalogue number: SMC-105A
Reactivities: Human, Mouse, Rat, Bovine, Canine, Chicken/Bird, Guinea Pig, Hamster, Horse, Porcine, Rabbit, Sheep
Hosts: Rat
Applications: Immunoprecipitation, Western Blot
Size: 50ug
Clone: 9G10
Accession: NP_003290.1
Gene: 7184
Swiss prot: P14625
Dilutions: 0.5ug/ml was sufficient for detection of Grp94 in 20ug of HeLa lysate.
Form: Protein G Purified
Storage buffer: PBS pH7.2, 50% glycerol
Concentration: 1mg/mL
Isotype: IgG2a
Shipping temp: Blue Ice or 4
Storage temp: -20
Research area: Heat Shock
Certificate of analysis: 0.5 ug/mL of SMC-105 was sufficient for detection of Grp94 in 20ug of heat shocked HeLa cell lysate by colorimetric immunoblot analysis using Goat anti-rat IgG:HRP as the secondary antibody.
Scientific background: Grp94 (glucose regulated protein 94, gp96) is a constitutively expressed endoplasmic reticulum (ER) lumenal protein that is up-regulated in response to cellular stress such as heat shock, oxidative stress or glucose depletion. Grp94 is thought to play a r
Alternative names: HSP90B1, GP96, TRA1, ECGP
References: 1. Rudolph R.W., and Bedows E. (1997) J Biol Chem 272: 3125-3128. 2. Srivastava P.K., et al. (1994) Immunogenetics. 39(2):93- 98. 3. Mazzarella R.A., and Green M. (1987) J Biol Chem 262: 8875-8883. 4. Kang, H.S. and Welch W.J. (1991) J Biol Chem 266(9): 5