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Products Rho, 4D2
| Catalogue number: | SMC-176C |
| Reactivities: | Rat |
| Hosts: | Mouse |
| Applications: | ELISA, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot |
| Size: | 25ug |
| Clone: | 4D2 |
| Accession: | NP_000530.1 |
| Gene: | 6010 |
| Swiss prot: | P08100 |
| Dilutions: | 1:1000 (WB) |
| Form: | Protein G Purified |
| Storage buffer: | PBS pH7.4, 50% glycerol |
| Concentration: | 1mg/mL |
| Isotype: | IgG1 |
| Shipping temp: | Blue Ice or 4 |
| Storage temp: | -20 |
| Research area: | Signaling, GTPase |
| Certificate of analysis: | 1 ug/mL of SMC-176 was sufficient for detection of rhodopsin in 10ug of rat eye lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Scientific background: | Rhodopsin consists of the protein moiety opsin and a reversibly covalently bound cofactor, retinal. Opsin, a bundle of seven membrane embedded alpha-helices, binds retinal, a photoreactive chromophore, in a central pocket (2, 3). In addition to being the |
| Alternative names: | OPN2, opsd, opsin 2, opsin 2 rod pigment, opsin2, RHO, RP4, MGC138309, Retinitis Pigmentosa 4 |
| References: | 1. Molday R.S., Hicks D., and Molday L. (1987) Invest Ophthalmol Vis Sci. 28: 50-61. 2. Ridge K.D., Lee S.S.J., and Abdulaev N.G. (1996) J of Biol Chem. 271: 7860-7867. 3. Matsuyama T., Yamashita T., Imai H. and Shichida Y. (2009) J Biol Chem. Manuscript |
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