Macrophage Inflammatory Protein-1 alpha (MIP-1 alpha ), also known as CCL3, is produced by macrophages and is thought to induce inflammatory responses, including superoxide production by neutrophils. MIP-1 alpha can exist as a naturally occurring heterodimer with MIP-1 beta and has been shown to have antiviral activity against HSV-1. Recombinant MIP-1 alpha is a nonglycosylated Protein, containing 69 amino acids, with a molecular weight of 7.8 kDa.
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