Interleukin-22 (IL-22), also called IL-TIF, is an IL-10 family member, produced by activated dendritic cells and T lymphocytes. IL-22 signals via the IL-22R and IL-10Rbeta receptors to act as a potent mediator of the cellular inflammatory response. Recombinant IL-22 is a non-disulfide-linked homodimer, containing two 146 amino acids, with a total molecular weight of 33.6 kDa.
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