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NR2B glutamate receptor, S59-20

NR2B glutamate receptor, S59-20

Cat no: SMC-333D


Supplier: StressMarq Biosciences Inc.
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Detects ~166kDa. No cross-reactivity against NR2A
Catalogue number: SMC-333D
Reactivities: Human, Mouse, Rat
Hosts: Mouse
Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100ug
Clone: S59-20
Accession: NP_036706.1
Gene: 24410
Swiss prot: Q00960
Dilutions: 1ug/mL (WB), 0.1-1ug/mL (IHC/ICC), 1-10ug/mL (IF)
Form: Protein G Purified
Storage buffer: PBS pH7.4, 50% glycerol
Concentration: 1mg/mL
Isotype: IgG2A
Shipping temp: Blue Ice or 4
Storage temp: -20
Research area: Ion Channels
Certificate of analysis: 1ug/mL of SMC-333 was sufficient for detection of NR2B in 10ug of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Scientific background: NR2B containing receptors have been implicated in synaptic plasticity, memory formation and pain modulation (3). Studies suggest that the NR2B subunit of glutamate receptors may be potential targets for relieving pain; NR2B may be a probable target for an
Alternative names: NMDAR2B, hNR3, MGC142180, glutamate receptor subunit epsilon-2, NR3
References: 1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA. 2. www.iochannels.org 3. Zhuo M. (2009) Mol Brain. 2(1): 4 4. Gurwitz D, and Weizman A. (2002) Drug Discovery Today, 7(7): 403-406.